There are over 100 trillion microorganisms in the gut, which are thought to play a signiﬁcant role in various aspects of overall health. In this review article, researchers suggest that the connection between the brain and gut may be associated with the development of Alzheimer’s disease because the gut microbiota may induce inﬂammation throughout the body, potentially provoking cognitive impairment. Recent studies have found that the composition of the gut microbiome signiﬁcantly diﬀers between those with and without Alzheimer’s disease. Diet also has a strong impact on the gut microbiome, hence aﬀecting the risk of developing Alzheimer’s disease. In particular, following a Mediterranean diet is associated with a slower cognitive degeneration. On the other hand, the Western diet which contains high added sugar, processed meat, reﬁned grains, and saturated fats is associated with greater inﬂammation.
Nutrients. 2021 Jan 25;13(2):361. Published 2021 Jan 25. doi:10.3390/nu13020361 (Leblhuber F et al.)