Researchers have given us yet another reason to fill our plates with fruits, vegetables, whole grains, legumes, olive oil, and nuts! A European study followed more than 2,500 Greek adults for over a decade, tracking their medical records, lifestyle habits, and eating patterns. Those who most closely followed the Mediterranean Diet were 47% less likely to get heart disease, regardless of their smoking habits, age, family history, or other lifestyle factors. The scientists estimate that every one-point increase on the Mediterranean Diet score (a measure of how closely participants followed the Mediterranean Diet, on a scale of 1 to 55) is associated with a 3 percent drop in heart disease risk, so every little bit counts. In fact, the researchers found that the Mediterranean Diet was even more protective against heart disease than physical activity!
Presentation at the American College of Cardiology’s 64th Annual Scientific Session. San Diego CA. March 15, 2015.

Colorectal cancer is the leading cause of cancer mortality, so learning more about dietary prevention is an important area of research. Scientists at Loma Linda University in California analyzed food patterns and health data from over 77,000 adults for an average of 7 years. After controlling for demographic and lifestyle factors (including age, smoking, physical activity, and family history), the researchers found that those who ate vegetarian diets had an approximately 20% lower risk of colorectal cancer compared with nonvegetarians. Researchers also found that pesco-vegetarians in particular (vegetarians who eat fish) had a much lower risk of colorectal cancer. These results support other studies linking the Mediterranean diet (a plant-based diet that features fish) with a decreased risk for colorectal cancer.
JAMA Internal Medicine. 2015 March 9. [Epub ahead of print] (Orlich MJ et al.)

The Mediterranean diet is not as pervasive in Mediterranean nations as it once was, but research indicates that adopting this traditional pattern of eating could have widespread benefits. Researchers in Turkey analyzed the eating habits of 900 adults without heart disease, then monitored their health for 5 years. Men and women most closely following a Mediterranean diet were significantly less likely to have a heart attack or need a stent to open up their blood vessels. Additionally, the men most closely following a Mediterranean diet had significantly lower rates of coronary artery disease (the most common type of heart disease) and coronary bypass grafts (surgery to improve blood flow to the heart). However, in women, the lower rates of coronary artery disease and coronary bypass grafts were not statistically significant.
International Journal of Clinical and Experimental Medicine. 2015 Feb 15;8(2):2860-6. (Hoscan Y et al.)

Ventricular hypertrophy, or the thickening and enlargement of heart ventricles due to the accumulation of scar tissue, is thought to be a root cause of many heart ailments. To investigate how diet relates to this condition, researchers analyzed eating patterns and left ventricular mass (the size of the left ventricle of the heart, where enlargement is most common) of over 1,700 adults without history of heart attack or stroke. The scientists found that those most closely adhering to a Mediterranean Diet had a left ventricular mass that was 4% less than the rest of the study population, a reduction greater than that observed in people with moderate-to-heavy physical activity (another factor that supports heart health). In fact, for each point increase on the Mediterranean Diet Score (0-9), left ventricular mass was 1.98g lower (average left ventricular mass was 189g).
American Journal of Cardiology. 2015 Feb 15;115(4):510-4. (Gardener H et al.)

A worthy star of the Mediterranean diet, olive oil gains much of its prestige from the various antioxidants that it contains. To see how one of these antioxidants affects cancer growth, New York scientists extracted oleocanthal (OC), a compound in extra virgin olive oil, and applied it to a variety of cancer cells.  According to the scientists, “Amazingly, OC induced cell death in all cancer cells examined – as rapidly as 30 minutes after treatment,” but did not cause cell death in noncancerous cells. This finding opens up a new field in the area of cancer research, as scientists are eager to find more ways to treat and prevent this devastating disease. While guzzling olive oil is by no means a cure for cancer, these findings support existing research that enhancing your meals with olive oil is a delicious and nutritious practice to build a long and healthy life.
Molecular and Cellular Oncology. 2015 Jan 23. [Epub ahead of print] (LeGendre O et al.)

Puglia is a beautiful region in Southern Italy. In this article, researchers use Puglia as an example of the Mediterranean diet’s connection between both good taste and good health, highlighting typical, nutritionally balanced dishes (such as fave bianche e cicorie, orecchiette e cime di rapa, soup of pulses and whole wheat, savory anchovy pie, and salads). The authors also analyze the climate and vegetation of the region, noting that the abundance of olive oil and wheat, and the wide assortment of interesting local vegetables helps contribute to this mostly plant-based diet.
International Journal of Gastronomy and Food Science. 2015 January;2(2):63-71. doi.org/10.1016/j.ijgfs.2014.12.001. (Renna M et al.)

Telomeres, DNA sequences at the end of chromosomes, can tell us a lot about aging and longevity, as shorter telomeres are associated with many age related diseases, such as heart disease and cancer. To determine the relationship between DNA and diet, Harvard researchers analyzed food intake and telomere length from over 4,600 healthy nurses using data from the Nurses’ Health Study. Researchers found that people with the greatest adherence to the Mediterranean Diet (lots of vegetables, fruits, grains (mostly unrefined), fish, legumes, and nuts, and less meat) had the longest telomeres, a good indicator of healthy aging. Additionally, the scientists pointed out that no one specific food was pinpointed as the best, reinforcing the importance of a well-rounded, healthy diet.
British Medical Journal. 2014 Dec 2;349. (Crous-Bou M et al.)

Chronic inflammation (the body’s response to stress) is linked with a number of diseases. To see how diet may play a role, Spanish researchers reviewed data on the Mediterranean diet and inflammatory disease, and found that following a Mediterranean diet is linked with both short and long term benefits for inflammatory diseases. In the short term, Mediterranean diets can help reduce risk factors associated with cardiovascular disease, like blood pressure and cholesterol. But the benefits of following a Med diet persist over time. In the long term, following this eating pattern has an intense, systemic, anti−inflammatory effect. This suggests that adherence to a Mediterranean diet may help protect against diseases like atherosclerosis, cancer, and neurodegenerative diseases, such as Alzheimers disease.
Endocrine, Metabolic & Immune Disorders−Drug Targets. 2014 Nov;14:245−254. (Casas R et al.)

Our kidneys have many important functions; besides filtering waste, they help control blood pressure, help make red blood cells, and more. The eGFR (estimated glomular filtration rate) is a blood lab that is used to assess kidney function, as low eGFR levels can indicate kidney damage or even kidney failure. In a 15 year study following  900 adults (free of stroke and coronary artery disease), researchers analyzed diet and eGFR status. The researchers found that people most closely following the Mediterranean Diet were least likely to have a low eGFR, and least likely to have a high rate of eGFR decline (which would have indicated a worsening of kidney function).
Clinical Journal of the American Society of Nephrology. 2014 Nov 7;9(11). (Khatri M et al.)