Telomeres, DNA sequences at the end of chromosomes, can tell us a lot about aging and longevity, as shorter telomeres are associated with many age related diseases, such as heart disease and cancer. To determine the relationship between DNA and diet, Harvard researchers analyzed food intake and telomere length from over 4,600 healthy nurses using data from the Nurses’ Health Study. Researchers found that people with the greatest adherence to the Mediterranean Diet (lots of vegetables, fruits, grains (mostly unrefined), fish, legumes, and nuts, and less meat) had the longest telomeres, a good indicator of healthy aging. Additionally, the scientists pointed out that no one specific food was pinpointed as the best, reinforcing the importance of a well-rounded, healthy diet.
British Medical Journal. 2014 Dec 2;349. (Crous-Bou M et al.)

Chronic inflammation (the body’s response to stress) is linked with a number of diseases. To see how diet may play a role, Spanish researchers reviewed data on the Mediterranean diet and inflammatory disease, and found that following a Mediterranean diet is linked with both short and long term benefits for inflammatory diseases. In the short term, Mediterranean diets can help reduce risk factors associated with cardiovascular disease, like blood pressure and cholesterol. But the benefits of following a Med diet persist over time. In the long term, following this eating pattern has an intense, systemic, anti−inflammatory effect. This suggests that adherence to a Mediterranean diet may help protect against diseases like atherosclerosis, cancer, and neurodegenerative diseases, such as Alzheimers disease.
Endocrine, Metabolic & Immune Disorders−Drug Targets. 2014 Nov;14:245−254. (Casas R et al.)

Our kidneys have many important functions; besides filtering waste, they help control blood pressure, help make red blood cells, and more. The eGFR (estimated glomular filtration rate) is a blood lab that is used to assess kidney function, as low eGFR levels can indicate kidney damage or even kidney failure. In a 15 year study following  900 adults (free of stroke and coronary artery disease), researchers analyzed diet and eGFR status. The researchers found that people most closely following the Mediterranean Diet were least likely to have a low eGFR, and least likely to have a high rate of eGFR decline (which would have indicated a worsening of kidney function).
Clinical Journal of the American Society of Nephrology. 2014 Nov 7;9(11). (Khatri M et al.)

Metabolic syndrome is a dangerous cluster of 3 or more conditions: central obesity (storing fat around your middle), high blood pressure, high triglycerides (a type of fat in your blood), high LDL (bad) cholesterol, low HDL (good) cholesterol, and high blood sugar. Metabolic syndrome greatly increases your risk for heart disease and diabetes, but luckily, researchers found a delicious way to reverse the condition. Scientists in Spain reviewed data collected during the PREDIMED study in which over 7,400 adults at risk of heart disease were randomly assigned to eat 1 of 3 diets: Mediterranean Diet supplemented with extra-virgin olive oil, Mediterranean Diet supplemented with nuts, or a control diet (patients received advice on a low-fat diet). Researchers found that while the Mediterranean diet was not associated with the onset of metabolic syndrome, reversal of the condition (decrease in central obesity and/or high blood sugar) occurred in nearly one third of patients eating either version of the delicious and nutritious Mediterranean diet.
Canadian Medical Association Journal. 2014 Oct 14. Pii:cmaj.140764. [Epub ahead of print] (Babio N et al).

We’ve long known that a Mediterranean inspired diet rich in olive oil is associated with disease prevention, but recent studies are showing promise in disease treatment as well. In an animal study at the University of Illinois, either palmitate (the dietary fat found in animal fats, dairy, and palm oil) or oleate (the dietary fat found in olive oil) was delivered directly to beating rat hearts with heart failure. The palmitate treated hearts continued failing, with depressed fat metabolism and storage. On the other hand, the oleate treated hearts greatly improved, with restored fat content in cells, improved contraction, and normalized fat metabolism genes. In fact, after observing the hearts treated with oleate, the scientists declared that the fat content, turnover, and oxidation in the failing hearts “were indistinguishable from those of the healthy heart.”
Circulation. 2014 September 29, pii [Epub ahead of print] (Lahey R et al.)

Diets high in fruits and vegetables have long been associated with a decreased risk of many cancers. In a recent European case controlled study, scientists investigated 2 years of self-reported dietary intakes of 768 people with incident cases of mouth cancer, and 2078 people with no history of mouth cancer. The food intakes were then evaluated for adherence to the Mediterranean Diet. After analyzing the data, researchers found strong evidence that those with the highest adherence to the Mediterranean Diet had the lowest risk for mouth cancer.
British Journal of Cancer. 2014 August 26;111(5):981-6 (Filomeno M. et al.)

Researchers in Vienna, Austria reviewed data from over 122,000 adults to investigate the association between the Mediterranean diet and diabetes risk. After analyzing eight prospective cohort studies and one clinical controlled trial published between 2007 and 2014, the scientists found that greater adherence to a Mediterranean diet is associated with a significant reduction (19%) in the risk of type 2 diabetes.
Public Health Nutrition. 2014 Aug 22 [Epub ahead of print] (Schwingshackl L et al.)

Although environmental factors are related to asthma very little research exists on asthma and dietary patterns. Stanford researchers conducted a systematic review and meta-analysis of 31 studies on asthma and diet. While the analysis found no association between diet and asthma prevalence in adults or of maternal diet with child asthma or wheeze, 7 of the 10 studies analyzing the Mediterranean diet showed protective effects on child asthma and/or wheeze. This research suggests that the Mediterranean diet may prevent asthma or wheeze in children.
Journal of Asthma and Allergy. 2014 Aug 12;7:105-21 (Lv N et al.)

The Mediterranean diet stands the test of time! As part of a prospective cohort study in Spain, researchers assessed 1815 community dwelling older adults for adherence to the Mediterranean diet and measures of frailty (including exhaustion, muscle weakness, low physical activity, slow walking speed, and weight loss). The researchers found that greater adherence to the Mediterranean diet was significantly associated with a decreased risk of frailty. The study also found that reduced frailty risk was related with increased fruit consumption and fish consumption.
Journal of the American Medical Directors Association. 2014 Aug 7 (Leon-Munoz LM et al.)