Lupus, an autoimmune disease in which the immune system attacks its own tissues, affects an estimated 1.5 million Americans. In this study, researchers analyzed the eating patterns and health markers of 280 people with systemic lupus erythematosus, the most common type of lupus. Those most closely following a Mediterranean diet were significantly more likely to have lower lupus disease activity and damage accrual and were also significantly more likely to have fewer heart disease risk factors. Additionally the odds of having active lupus or the presence of damage was significantly lower among people who most closely followed a Mediterranean diet.
Rheumatology (Oxford). 2021 Jan 5;60(1):160-169. doi: 10.1093/rheumatology/keaa210. (Pocovi-Gerardino G et al.)

A growing body of research demonstrates the Mediterranean diet’s relationship with healthy aging. This British study focused on 511 individuals whose average age was 79 years old. The scientists collected data on eating habits and brain health from the participants. They found that those who more closely follow a Mediterranean diet are more likely  to have overall better cognitive function, including better memory, visuospatial ability, and verbal ability. Furthermore, the study found that eating more  green leafy vegetables and lessmeat may be linked withbetter cognitive performance. 
Experimental Gerontology. 2020 Dec; 142:111117. doi:10.1016/j.exger.2020.111117. (Corley J et al.)

Maintaining a healthy weight and healthy blood sugar control are thought to help prevent chronic diseases down the road. In a study of 142 adults, people who most closely followed a Mediterranean diet were more likely to have less body fat, better fasting blood sugar, lower insulin, and lower triglycerides (a type of fat in the blood). Other measured health differences between those who followed the Mediterranean diet and those who didn’t were not statistically significant.
Postgrad Medical Journal. 2020 Nov 12;postgradmedj-2020-138667. doi: 10.1136/postgradmedj-2020-138667. (Kalkuz S et al.)

The Mediterranean diet is linked with a lower risk of diabetes, and researchers want to learn more about the mechanisms behind this protective effect. This study followed up a group of 25,317 middle-aged women without diabetes for approximately 20 years. The results indicated that those who strictly follow the Mediterranean diet tend to have a 30% lower risk of developing type 2 diabetes compared to those who don’t follow a Mediterranean diet. The lower risk of diabetes could be partially explained by better insulin resistance, lower inflammation, and lower cholesterol in the women who followed a Mediterranean diet, and the results were especially strong in people who were overweight at the beginning of the study.
JAMA Network Open. 2020 Nov 2; 3(11):e2025466. doi:10.1001/jamanetworkopen.2020.25466 (Ahmad S et al.)

Erectile dysfunction can burden health-related quality of life for both the affected men and their partners. In a study of 21,469 men in the U.S., both younger men (under 60) and older men (60+) most closely following a Mediterranean diet had a 22% and 12% lower risk of experiencing erectile dysfunction, respectively. Likewise, men eating an overall healthy diet (as measured by the Alternative Healthy Eating Index 2010) also were significantly less likely to experience erectile dysfunction.
JAMA Network Open. 2020 Nov 2;3(11):e2021701. doi:10.1001/jamanetworkopen.2020.21701. (Bauer SR et al.)

Prodromal Parkinson’s disease is when someone does not meet the full diagnostic criteria for having Parkinson’s disease, but they do exhibit some Parkinson’s symptoms and are at increased risk of being diagnosed with Parkinson’s down the road. In this study, researchers analyzed the diets of 17,400 adults and monitored them for signs of prodromal Parkinson’s disease. Those most closely following a Mediterranean diet were significantly less likely to have symptoms of prodromal Parkinson’s disease.
Neurology. 2020 Oct 13;95(15):e2095-e2108. doi: 10.1212/WNL.0000000000010523. Epub 2020 Aug 19. (Molsberry S et al.)

The secret to longer life just might be in your kitchen. A large study of 5,094 Italian men was conducted over a seven-year period to see how their daily diets and lifestyle habits affected mortality rates. Those most closely following the Mediterranean diet were less likely to die over the study period. Additionally, the researchers also found a significant relationship between lower death risk and eating higher amounts of vegetables, proteins, fats, starch, folic acid, and monounsaturated fats from plant-based sources (mostly from olive oil). On the other hand, animal fats and sugar were linked with a greater risk of death over the study period.
Nutrition, Metabolism, and Cardiovascular Diseases. 2020 Sept 24;30(10):1673-1678. doi.10.1016/j.numecd.2020.05.034 (Trevisan M et al.)

The endothelium lines the heart and blood vessels, and when not working properly, can be an indicator of atherosclerosis (dangerous buildup of fatty plaques in arteries). In this study, researchers randomly assigned 805 adults with coronary heart disease to a Mediterranean diet or a low-fat control diet and measured their endothelial function. After 1 year on their respective diets, those following a Mediterranean diet were more likely to have improved endothelial function and better homeostasis of their blood vessels, even in patients with severe endothelial dysfunction.
PLoS Medicine. 2020 Sep 9;17(9):e1003282. doi: 10.1371/journal.pmed.1003282. eCollection 2020 Sep. (Yubero-Serrano EM et al.)

A Mediterranean diet based on vegetables, fruits, whole grains, fish, olive oil, beans, and fermented dairy is a delicious blueprint for good health. However, lifestyle elements in addition to diet can also make a difference. In a study of 92 (mostly male) firefighter recruits in New England, those who most closely follow a Mediterranean lifestyle (as defined by eating a Mediterranean diet, adequate sleep, lower screen time, lower BMI, exercising, and not smoking) were significantly less likely to have high blood pressure, and were significantly more likely to have better aerobic capacity (a measure of the ability to provide oxygen to muscles).
Journal of Occupational and Environmental Medicine. 2020 Jul;62(7): 466–471. doi: 10.1097/JOM.0000000000001868 (Lan FY et al.)

Some of the worlds healthiest, longest lived people follow a Mediterranean diet, so researchers wonder about the mechanism behind its link with healthy aging. In this study, researchers analyzed the gut microbiome of 612 older European adults before starting a Mediterranean diet, and then after 1 year of following a Mediterranean diet. Those who followed the Mediterranean diet most closely had significant differences in their gut microbiome, including microbes associated with lower risk of frailty, better brain function, and lower inflammation.
Gut. 2020 Jul;69(7):1218-1228. doi: 10.1136/gutjnl-2019-319654. Epub 2020 Feb 17.

Eating a nutritious diet is one of the many daily lifestyle choices that can have an impact on our health, especially as we age. Researchers followed 2,765 adults in the Chicago area for over 5 years to see if their lifestyle choices were related to their risk of Alzheimer’s dementia. They specifically looked for these 5 healthy lifestyle factors: 1) not smoking, 2) at least 150 minutes per week of exercise, 3) low to moderate alcohol consumption, 4) following a Mediterranean-inspired healthy diet, and 5) participating in late-life “cognitive activities” like reading, crafting, playing games, and socializing. Compared with adults following 0 or 1 healthy lifestyle factor, the risk of Alzheimer’s dementia was 37% lower in those following 2 or 3 healthy lifestyle factors, and 60% lower in those following 4 or 5 healthy lifestyle factors.
Neurology. 2020 Jun 17;10.1212/WNL.0000000000009816. doi: 10.1212/WNL.0000000000009816. (Dhana K et al.)

Lockdowns and restaurant closures related to the global COVID-19 pandemic have swiftly changed the way people eat, leaving many people with little choice but to eat more home-cooked meals. Researchers analyzed the diets of 7,514 Spaniards during the COVID-19 pandemic, and also asked them about their eating habits before the pandemic. During the pandemic, when people were forced to eat more home-cooked meals, researchers noted that the Mediterranean diet score of these participants (a measure of how closely people follow the Mediterranean diet) significantly increased. The people who improved their diet reported eating more olive oil, vegetables, fruits, or legumes, and less fried foods, snacks, fast foods, red meat, pastries, or sweetened drinks. The authors conclude that, “this improvement, if sustained in the long-term, could have a positive impact on the prevention of chronic diseases and COVID-19-related complications.”
Nutrients. 2020 Jun 10;12(6):E1730. doi: 10.3390/nu12061730.(Rodríguez-Pérez C et al.)