Endometrial cancer, also known as womb cancer, is largely determined by hormone levels in the body. However, new research shows that diet can play an important role in prevention. Combining the results of three large studies, Italian researchers analyzed the eating patterns of over 5,000 women in Europe (1411 with endometrial cancer, and 3668 controls) for their adherence to the Mediterranean diet. Those most closely following the Mediterranean diet were over 50% less likely to develop endometrial cancer than those with the lowest adherence to the Mediterranean diet. Additionally, researchers found that “the Mediterranean diet as a whole is a stronger determinant of endometrial cancer risk than the single dietary components,” emphasizing the importance of overall diet.
British Journal of Cancer. 2015 May 26;112(11):1816-21. (Filomeno et al.)
Minorities and low-income populations are often underrepresented in nutrition studies, but new research indicates that healthy diets with whole grains can benefit all of us, including underserved populations. In this study, researchers examined the diets and medical records of over 77,000 people from 12 states in the southeastern US, most of whom were low-income and African American. Researchers found that those most closely adhering to a healthy diet (including at least 1 ½ servings of whole grains per day) had a 14-23% lower death rate from all diseases, heart disease, cancer, and more. Additionally, while overall dietary patterns are the best way to assess health, whole grains specifically were associated with a lower death risk (as were dairy, seafood, and plant proteins).
PLOS Medicine. 2015 May 26;12(5):e1001830; discussion e1001830. (Yu D et al.)
Nuts have long been associated with longevity, and new research in diverse populations further supports this relationship. Researchers tracked peanut and nut intake of about 206,000 people in the US (low income blacks and whites) and China for over 5 years. High nut intake was associated with a 21% lower risk of death from all causes among the US participants, and a 17% lower risk in the Chinese participants. High nut and peanut intake was also associated with a lower risk of death from heart disease, especially in ischemic heart disease (the type of heart disease caused by narrowed arteries).
JAMA Internal Medicine. 2015 May;175(5):755-66. (Luu HN, et al.)
The Mediterranean diet has long been studied for its role in heart health and aging, but emerging research suggests that it may also be protective for brain health. In a follow up to the PREDIMED study (where Spanish adults at risk for heart disease were randomly assigned to either a Mediterranean diet with four tablespoons of olive oil daily, a Mediterranean diet with one ounce of nuts daily, or a low fat controlled diet) researchers analyzed the relationship between diet and cognitive function. Of the 334 participants in this study with data on cognitive function, the scientists found that overall brain function significantly improved for both Mediterranean groups over the 4-year experiment, compared with the control group. Specifically, the nuts group significantly improved on tests of memory, while the olive oil group significantly improved on tests of reasoning, planning, and problem solving. This adds to the growing body of research that the Mediterranean diet is an important factor in healthy aging.
JAMA Internal Medicine. 2015 May 11. [Epub ahead of print] (Valls-Pedret C et al.)
Colon cancer, the second leading cause of cancer death in the US, affects a greater proportion of African Americans than rural Africans, indicating that diet plays an important role in disease prevention. To see how traditional diets affect risk factors for colon cancer, researchers assigned 20 middle aged African Americans to a traditional, African heritage diet (averaging 55g fiber daily and 16% calories from fat, with foods like mangos, bean soup, and fish) and 20 middle aged rural South Africans to a typical American diet (averaging 12g fiber daily and 52% calories from fat, with foods like pancakes, burgers, fries, and meatloaf). In just 2 short weeks, the African Americans reduced the inflammation of their colons, improved their markers for cancer (including increased levels of butyrate, an anti-cancer chemical), and increased the diversity of their healthy gut bacteria. On the other hand, the rural Africans eating an American diet fared worse, producing more bile acid (a risk factor for colon cancer), while decreasing the diversity of healthy gut bacteria. These results indicate that an African heritage diet can help promote a healthy digestive tract (potentially reducing colon cancer risk), and that rapid improvements can come with a change to healthier foods.
Nature Communications. 2015 Apr 28;6:6342. (O’Keefe SJ et al.)
Eating whole grains daily may help keep breast cancer at bay. Approximately 1 in 8 women are diagnosed with breast cancer, and lifestyle factors are thought to play an important role in prevention. To determine the relationship between eating patterns and breast cancer, researchers analyzed the diets of 250 newly diagnosed female breast cancer patients, and 250 age-matched controls (without cancer). The scientists found that eating whole grains at least 7 times per week was associated with a decreased risk of breast cancer.
Journal of the American College of Nutrition. 2015 Apr 27:1-7 [Epub ahead of print] (Mourouti N et al.)
Sardinia, Italy has gained international recognition as one of the world’s longevity Blue Zones, as it has a large concentration of people who live exceptionally long lives. To determine how the traditional Sardinian diet might play a role in longevity, European researchers analyzed the traditional eating habits of Sardinia based on works published over a century. Researchers characterize the traditional Sardinian diet as “remarkably frugal.” Foods native to the Sardinian diet include grains (wheat and barley), potatoes, pulses, sheep milk and goat milk and their fresh cheeses, wild fruits, and fresh vegetables, with fermented whole grain breads and minestrone soup making up a substantial portion of the diet prior to the 1950’s. After the mid-1950’s, Sardinians were able to eat more meat and pasta, along with more fresh vegetables, olive oil, and fish, but with fewer potatoes, pulses, and less lard. The researchers conclude that this unique combination of diets may attribute to the exceptionally long lifespan of Sardinians born at the end of the 19th century, and are eager to monitor the lifespan of future generations of Sardinians.
European Journal of Clinical Nutrition. 2015 Apr;69(4):411-8. (Pes GM et al.)
Dairy foods are most often prized for their calcium content, but new research reveals that changes to the gut microbiome, especially from eating fermented dairy products, like cheese, might help explain the “French Paradox,” the phenomenon in which traditional cheeses are linked with low rates of heart disease. In a small study to investigate the protective effect of dairy foods, Danish scientists randomly assigned 15 healthy men to one of three diets for two weeks: a diet with lots of partly skim (1.5%) milk, a diet with lots of semi-hard cow’s cheese, or a control diet with butter, but no other dairy products. Both the milk and cheese diets had the same amount of calcium per day (1.7g). The men rotated through each diet, with a two-week washout period in between each new diet group. Compared to the control diet, both the cheese and milk diets were associated with significantly lower production of TMAO, a compound that is thought to be a marker of heart disease risk. The researchers also found that “dairy consumption, especially cheese, can beneficially modify the gut microbiota to increase SFCA levels.” SFCAs (short chain fatty acids) are compounds produced by gut bacteria that are linked with many health promoting effects, such as lower risk of diabetes, heart disease, and inflammatory diseases.
Journal of Agricultural and Food Chemistry. 2015 Mar 18;63(10):2830-9 (Zheng H et al).
One of the great ironies of the healthcare system is that doctors are often untrained in the most basic of wellness practices: nutrition. In a survey of 236 physicians at a large US medical center (including cardiologists and internal medicine doctors and trainees), fewer than 14% felt adequately trained to discuss nutrition with their patients. Nearly all doctors (90%) recognized the Mediterranean Diet as protective against heart disease, but fewer than half (46%) realized that low-fat diets have not been proven to reduce heart disease risk. Additionally, many doctors had trouble identifying foods high in various nutrients, such as which fish are high in omega-3 fatty acids. These data highlight the importance of making reliable nutrition resources (specifically those relating to well researched eating patterns, such as the Mediterranean diet) available to the medical community. (Note: If you’re a healthcare professional who would like to learn more about the Mediterranean Diet, see here.)
Presentation at the American College of Cardiology’s 64th Annual Scientific Session. San Diego CA. March 15, 2015.
Researchers have given us yet another reason to fill our plates with fruits, vegetables, whole grains, legumes, olive oil, and nuts! A European study followed more than 2,500 Greek adults for over a decade, tracking their medical records, lifestyle habits, and eating patterns. Those who most closely followed the Mediterranean Diet were 47% less likely to get heart disease, regardless of their smoking habits, age, family history, or other lifestyle factors. The scientists estimate that every one-point increase on the Mediterranean Diet score (a measure of how closely participants followed the Mediterranean Diet, on a scale of 1 to 55) is associated with a 3 percent drop in heart disease risk, so every little bit counts. In fact, the researchers found that the Mediterranean Diet was even more protective against heart disease than physical activity!
Presentation at the American College of Cardiology’s 64th Annual Scientific Session. San Diego CA. March 15, 2015.
