Mediterranean diets have been linked with brain health and lower dementia risk in small studies, but researchers wanted to see how this relationship holds up in larger studies and in people who are genetically predisposed to dementia. In a study of 60,298 older adults in the UK, those most closely following a Mediterranean diet were 23% less likely to develop dementia over the 9 year study period, independent of a person’s genetic risk for dementia.
BMC Med. 2023 Mar 14;21(1):81. doi: 10.1186/s12916-023-02772-3. (Shannon OM et al.)

Brain-healthy diets include a variety of healthy ingredients, and researchers wonder if whole grains specifically might be related to dementia risk. In a study of 2,958 adults in the U.S., those eating the most whole grains were 28% less likely to develop all-cause dementia and were 36% less likely to develop Alzheimer’s dementia over the 12-year study period. The researchers note that more research is needed to better understand this relationship.
J Prev Alzheimers Dis. 2023;10(1):133-136. doi: 10.14283/jpad.2022.91. (J Wang et al.)

Adverse pregnancy outcomes (such as preeclampsia, eclampsia, gestational hypertension, gestational diabetes, preterm birth, small-for-gestational age, and stillbirth) can put both mothers and babies at risk. In this prospective study of 7,798 pregnant women across the US, those most closely following a Mediterranean diet were 21% less likely to develop any of the adverse pregnancy outcomes described above and were also 28% less likely to develop preeclampsia and 37% less likely to develop gestational diabetes. The researchers noted a dose-response relationship for risk of adverse pregnancy outcomes, meaning that the closer a mother’s diet aligned with the Mediterranean diet, the lower the risk.
JAMA Netw Open. 2022 Dec 1;5(12):e2248165. doi: 10.1001/jamanetworkopen.2022.48165.

Frailty in aging may lead to falls, fractures, disability, and other serious health risks, so dietary strategies to prevent frailty in older adults are of great importance. In a study of 2,384 nonfrail adults from the Framingham Offspring Study (average age 60 years), those most closely following a Mediterranean diet had a 38% lower risk of developing frailty than those not adhering to a Mediterranean diet. Additionally, each 10-mg increase of total carotenoids and vitamin E (antioxidants found in many Mediterranean diet foods) reduced the risk of frailty by 16%.
Am J Clin Nutr. 2022 Sep 2;116(3):630-639. doi: 10.1093/ajcn/nqac130. (Millar et al.)

In this study, researchers surveyed 348 registered dietitians and 124 nutrition students about whole grain foods. Both groups had high whole grain knowledge and were able to correctly identify whole grain foods. The authors note that exposure to whole grain foods plays a critical role in behavior change, and that “the use of prominent and clear whole-grain labeling should be increased, such as the Whole Grain Stamp.”
Nutrition Today. 2022 July/Aug;57(4):200-208. (Hicks-Roof K et al.) doi: 10.1097/NT.0000000000000550

Meals served in the National School Lunch Program are developed with nutrition, cost, and youth preferences in mind, with little room or direction to consider environmental impact. Using data from over 2.2 million real-world lunches, researchers at Tufts quantified the environmental footprint of each lunch served to see if they could determine patterns and form recommendations for more sustainable lunches. They found that low impact school lunches had “20% more whole grains, nearly 20 times more nuts and seeds, and four times less animal protein than high impact lunches.” As a result, the authors concluded that “increasing whole grain requirements and providing serving size or frequency limits for beef” are the two most effective recommendations for reducing the environmental impacts of the National School Lunch program. 
Nature. 2022 June 23;3(138). doi: 10.1038/s43247-022-00452-3. (Stern AL et al.)

Healthy life expectancy is a measure of how long a person lives in “full health” without disease or injury. In an analysis of the diets and health outcomes of people in 130 countries around the world, following a Mediterranean diet was significantly associated with both life expectancy and healthy life expectancy even after controlling for things like socio-economic status and health indicators.
J Nutr Health Aging. 2022;26(6):621-627. doi: 10.1007/s12603-022-1811-y. (A Sezaki et al.)

Randomized controlled trials, in which people are randomly assigned to a particular treatment and then monitored over time, are considered by many to be the “gold standard” of nutrition research. In this randomized controlled trial, 1,002 Spanish adults (average age 59) with heart disease were randomly assigned to a Mediterranean diet or a control diet (which differed by emphasizing lean meats and fish and low-fat dairy, and restricting fatty fish, nuts and olive oil) and followed for 7 years. Those eating a Mediterranean diet were 25-29% less likely to have a major cardiovascular event (such as a heart attack or stroke) than those eating the control diet, with the relationship being especially strong in men. These findings are consistent with previous research noting the cardioprotective benefits of a Mediterranean diet. 
Lancet. 2022 May 4;S0140-6736(22)00122-2. doi: 10.1016/S0140-6736(22)00122-2. (Delgado-Lista J et al.)

Preeclampsia is a pregnancy complication characterized by a rapid rise in blood pressure. In this study, researchers surveyed a diverse cohort of Black, Hispanic, and white low-income mothers in Boston about their diet and searched their health records for diagnoses of preeclampsia. Greater adherence to the Mediterranean diet was linked with a 22% lower risk of preeclampsia overall, with significant risk reduction for each of the racial groups.
Journal of the American Heart Association. 2022 May 3;11(9):e022589. doi: 10.1161/JAHA.121.022589. (Minhas AS et al.)

Health economics, the practice of quantifying how much money could be saved by taking certain health promotion measures (such as eating more whole grains) is a growing area of research. In this study, researchers analyzed 4 different models for measuring the health savings of eating more whole grains to identify best practices and inform future research. They found that while results varied from one study to the next, each method identified substantial health savings if people were to make more of their grains whole. The authors recommend that future studies consider realistic behavior changes, which may vary from one country to the next.
Journal of Cereal Science. 2022 May. doi: 10.1016/j.jcs.2022.103455 (Miller KB et al.)​

Public-private partnerships include collaborations between governments, industry, and/or nonprofits to work towards a common objective, and can be a great strategy to make progress on population-wide goals, such as improving whole grain intake. In this study, researchers examined 3 of the most well-known whole grain public-private partnerships (the Oldways Whole Grains Council in the US, the Danish Whole Grain Partnership, and the Grains and Legumes Nutrition Council in Australia) to identify best practices for increasing whole grain intake globally. The study concludes that to successfully improve whole grain intakes in the long-term, public-private partnerships should address environmental sustainability, be incorporated into front-of-pack labeling schemes, and reach out those who eat the least amount of whole grain.
Journal of Cereal Science. 2022 May. doi: 10.1016/j.jcs.2022.103456 (Sluyter C et al.)

Diet and lifestyle are thought to play a role in the risk for neurodegenerative diseases like Alzheimer’s and Parkinson’s, and researchers wonder if the gut microbiome may modulate this relationship. A review of 64 studies analyzed the relationship between the Mediterranean diet and risk of Alzheimer’s disease and/or Parkinson’s disease, as well as the relationship between the makeup of the gut microbiome and its association with both diet and neurodegenerative diseases. Greater adherence to a Mediterranean diet was linked with a lower risk of both Alzheimer’s and Parkinson’s disease. The study also identified specific genera and species of bacteria that had an inverse relationship with the Mediterranean diet and these diseases, suggesting that the gut microbiota may play a role in this relationship.
J Neurol Sci. 2022 Mar 15:434:120166. doi: 10.1016/j.jns.2022.120166. (Solch RJ et al.)