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More Research Needed on Mediterranean Diet & Cognition

To get a better understanding of how the Mediterranean diet relates to brain health, researchers analyzed existing randomized controlled trials (the “gold standard” of nutrition research, where participants are randomly assigned to one diet or another, so that researchers can look for causal relationships). Thus far only 5 randomized controlled trials on the Mediterranean diet and cognition have been published, with mostly insignificant results. However, the researchers did note that the most well-designed studies (using PREDIMED data) are the studies that found a protective effect on dementia risk and cognition, indicating that the Mediterranean diet might hold promise in these areas. More research is needed.
American Journal of Clinical Nutrition. 2018 Mar 1;107(3):389-404. (Radd-Vagenas S et al.)

Both Mediterranean and Vegetarian Diets Effective for Weight Loss

From Mediterranean to vegetarian, many of the world’s healthiest diets actually have more similarities than differences, so it’s not surprising to find that both these diets can be an effective path to weight loss. In this study, researchers randomly assigned 118 overweight adults who normally eat meat to either a lower calorie Mediterranean diet or a lower calorie vegetarian diet for 3 months. After a two-week assessment, the participants then switched to the other diet for 3 months. Participants lost about 4 pounds during each diet, and both diets were also effective at decreasing body fat. The only significant difference between the diets was that the vegetarian was slightly more effective in lowering bad (LDL) cholesterol, while the Mediterranean diet was slightly more effective in lowering triglycerides (a type of fat in the blood).
Circulation. 2018 Feb 26. (Sofi F et al.) [Epub ahead of print]

Mediterranean Diet Linked with Lower Risk of Aggressive Prostate Cancer

Lifestyle habits, like diet, are an important part of a cancer-protective strategy. To see if diet relates to prostate cancer risk, researchers analyzed the eating habits of 754 men with prostate cancer, and 1,277 controls without prostate cancer. Those most closely following a Mediterranean diet were 34% less likely to have an aggressive form of prostate cancer than those not following a Mediterranean diet. A Western diet (filled with fast food, sweets, and red meat) and a prudent diet (filled with low fat dairy, juice, produce, and whole grains) were not found to be linked to prostate cancer risk.
Journal of Urology. 2018 Feb;199(2):430-437. (Castello A et al.)

Substituting Whole Grains for Refined Linked with Lower Risk of Death, Cancer Reoccurrence

The link between whole grains and colorectal cancer prevention is well established, but researchers wonder how this relationship plays out in patients who have already been diagnosed with colon cancer. In this study, researchers analyzed the eating habits and health status of 1,024 patients with stage III colon cancer. After 7 years, patients eating 3 or more servings of refined grains per day had a significantly higher risk of cancer reoccurrence or death from any cause. Replacing 1 serving of refined grains with 1 serving of whole grains daily was linked with a 23% lower risk of cancer reoccurrence or death from any cause. Eating 3 or more servings of whole grains daily trended towards lower risk as well, but the relationship was not statistically significant.
JNCI Cancer Spectrum. 2018 Feb;2(2):pky017. (Brown JC et al.)

Traditional Japanese Diets as a Cultural Model of Healthy Eating

Japan is famous for the long lifespan of its people, and the traditional diet is thought to play a role. In this review, researchers outline the healthful elements of traditional Japanese diets, including the variety of seasonal vegetables and seafood, umami flavors, cooking methods that incorporate water, modest portion sizes, and social and familial connections. They conclude that “Japanese traditional diet practices (Washoku), which prominently include the flavoring of foods with umami taste, can be characterized as a healthy diet in the same way that the DASH diet or the Mediterranean diet is so classified.”
Nutrients. 2018 Feb 3;10(2). pii: E173. (Gabriel AS et al.)

Mediterranean Diet May Help Improve Odds of a Successful Pregnancy in IVF

IVF, or in vitro fertilization (manually combining eggs and sperm in a lab, before transferring into the woman’s uterus) is a common treatment for couples struggling to have children, but researchers wonder whether diet might also play a role. In a study of 244 (non-obese) women in Greece who had their first in-vitro fertilization treatment, those most closely following a Mediterranean diet were significantly more likely to become pregnant and have a live birth than those not following a Mediterranean diet, but these results were only significant in women younger than 35. In fact, in women younger than 35, every 5-point increase in the Mediterranean Diet Score (0-55 scale) was linked with a nearly 3 times greater likelihood of getting pregnant and having a baby with IVF.
Human Reproduction. 2018 Jan 30. (Karayiannis D et al.) [Epub ahead of print]

Shifting the Wheat Breeding Process to Support Whole Grains

The infrastructure for wheat breeding & milling is largely set up to favor refined flour, rather than whole grain flour. In this article, researchers from Washington State University define new quality targets for wheat breeders that take into account fermentation, the bran and germ of the grain, protein strength, and flavor. They also note that different wheats are recommended for different products (pastry, breads, or noodles), and make recommendations for testing breeding lines on the farm to ensure that the new variety will work for farmers, millers, bakers, and consumers alike.
Agroecology and Sustainable Food Systems. 2018 January 29. (Jones SS et al.) [Epub]

Mediterranean-Inspired Diet May Slow Cognitive Decline in Stroke Survivors

Stroke survivors are twice as likely to develop dementia compared to the general population. To see how diet relates to brain health in stroke survivors, researchers analyzed the eating patterns and brain function of 106 stroke survivors for more than 4 years. Those most closely following a “MIND diet” had a slower rate of cognitive decline than those who don’t follow a MIND diet. The MIND diet is a hybrid Mediterranean-DASH diet that emphasizes foods associated with brain health, including whole grains, green leafy vegetables, berries, nuts, olive oil, and fish. The Mediterranean diet is well-known for its brain benefits, so it’s not surprising that this new diet inspired by the Mediterranean diet is also showing promise for brain health. 
Presentation at the American Heart Association Meeting. Los Angeles, California. January 25, 2018. 

Whole Grains Linked with Longer Lives

From Sardinia, Italy, to Nicoya, Costa Rice some of the longest-lived people in the world enjoy a diet filled with whole grains. To better understand this relationship, researchers analyzed data from 19 cohort studies encompassing more than one million participants. They found that each one-ounce daily serving of whole grains was associated with a 14% lower risk of death from heart disease, a 3% lower risk of death from cancer, and a 9% lower risk of total mortality.
European Journal of Clinical Nutrition. 2018 Jan;72(1):57-65. (Zhang B et al.)

Eating Fish Linked with Less Diabetic Eye Damage

Damage to the blood vessels in the eye (diabetic retinopathy) is a serious complication of diabetes that can lead to blurriness and blindness if untreated. In this study, researchers analyzed the eating patterns and eye health of 357 patients in Singapore with type 2 diabetes. Eating just one additional serving of fish per week is linked with a 9% lower likelihood of severe diabetic retinopathy. In patients without retinopathy, those eating more fish were more likely to have wider vascular caliber, an eye vessel measurement that can indicate a lower risk of chronic disease.
Scientific Reports. 2018 Jan 15;8(1):730. doi: 10.1038/s41598-017-18930-6. (Chua J et al.)

Great Potential for Using Teff in Food Products

Teff, a gluten-free grain native to the Horn of Africa, is best known as the base of injera bread, the spongy Ethiopian flatbread. Despite its huge potential, especially in gluten-free cuisine, teff products only make up a small percentage of the overall grain market. In this study, researchers analyze how teff affects the taste and texture of various food products, including bread, pasta, cookies, injera, and beverages. They also found that teff improves the nutrition of food products, providing fiber, iron, protein, and other essential nutrients, and note that teff is well-suited for harsh and dry environmental climates, like those found in India and China. In short, the authors conclude that “there is great potential to adapt teff to the other parts of the world for healthy food and beverage production.”
Food Chemistry. 2018 Jan 15;239:402-415. (Zhu F et al.)

Mediterranean Diet May Reduce Dependence on Multiple Meds

Polypharmacy occurs when patients have to take many medications at once, usually more than five daily medications. Because polypharmacy can result in confusion and frustration, low medication adherence, and ultimately increased health risk, especially in elderly populations, lifestyle changes to prevent or reduce polypharmacy are of great interest. To see how the Mediterranean diet relates to polypharmacy and cardiometabolic disorders like obesity and heart disease, researchers analyzed the diet, health conditions, and medications of 476 elderly adults in Rome. Those not following a Mediterranean diet (medium-low adherence) were more likely to need multiple medications, and have high blood pressure, unhealthy cholesterol levels, and diabetes. Looking at individual food components, olive oil, vegetables, fish, legumes, and nuts were all significantly related to a lower risk of polypharmacy. The authors conclude that following a Mediterranean diet “might potentially delay the onset of age-related health deterioration and reduce the need of multiple medications.”
The Journal of Nutrition, Health and Aging. 2018 Jan;22(1):73-81. (Vicinanza R et al.)