Health Studies

Med Diet Cuts Risk of Womb Cancer by Half

Endometrial cancer, also known as womb cancer, is largely determined by hormone levels in the body. However, new research shows that diet can play an important role in prevention. Combining the results of three large studies, Italian researchers analyzed the eating patterns of over 5,000 women in Europe (1411 with endometrial cancer, and 3668 controls) for their adherence to the Mediterranean diet. Those most closely following the Mediterranean diet were over 50% less likely to develop endometrial cancer than those with the lowest adherence to the Mediterranean diet. Additionally, researchers found that “the Mediterranean diet as a whole is a stronger determinant of endometrial cancer risk than the single dietary components,” emphasizing the importance of overall diet.
British Journal of Cancer. 2015 May 26;112(11):1816-21. (Filomeno et al.) 

Mediterranean Diet Can Improve Cognitive Function

The Mediterranean diet has long been studied for its role in heart health and aging, but emerging research suggests that it may also be protective for brain health. In a follow up to the PREDIMED study (where Spanish adults at risk for heart disease were randomly assigned to either a Mediterranean diet with four tablespoons of olive oil daily, a Mediterranean diet with one ounce of nuts daily, or a low fat controlled diet) researchers analyzed the relationship between diet and cognitive function. Of the 334 participants in this study with data on cognitive function, the scientists found that overall brain function significantly improved for both Mediterranean groups over the 4-year experiment, compared with the control group. Specifically, the nuts group significantly improved on tests of memory, while the olive oil group significantly improved on tests of reasoning, planning, and problem solving. This adds to the growing body of research that the Mediterranean diet is an important factor in healthy aging.
JAMA Internal Medicine. 2015 May 11. [Epub ahead of print] (Valls-Pedret C et al.) 

Leafy Greens Can Keep Your Brain Young

It is no secret that green vegetables are some of the healthiest foods for our bodies, but new research shows that they are also good for our brains. Researchers in Chicago and Boston analyzed the eating patterns and cognitive abilities of over 950 older adults for an average of five years. The scientists found a significant decrease in the rate of cognitive decline for people who ate more green leafy vegetables (like spinach, kale, collards, and mustard greens). In fact, people who ate just one to two servings of leafy greens per day had the cognitive ability of a person 11 years younger than those who ate none.

Presentation at the American Society for Nutrition (ASN) Annual Meeting during Experimental Biology. Boston MA. March 30, 2015.

Med Diet Cuts Heart Disease Risk by Nearly Half

Researchers have given us yet another reason to fill our plates with fruits, vegetables, whole grains, legumes, olive oil, and nuts! A European study followed more than 2,500 Greek adults for over a decade, tracking their medical records, lifestyle habits, and eating patterns. Those who most closely followed the Mediterranean Diet were 47% less likely to get heart disease, regardless of their smoking habits, age, family history, or other lifestyle factors. The scientists estimate that every one-point increase on the Mediterranean Diet score (a measure of how closely participants followed the Mediterranean Diet, on a scale of 1 to 55) is associated with a 3 percent drop in heart disease risk, so every little bit counts. In fact, the researchers found that the Mediterranean Diet was even more protective against heart disease than physical activity!
Presentation at the American College of Cardiology’s 64th Annual Scientific Session. San Diego CA. March 15, 2015.

Doctors May Not Be Equipped for Diet Counseling

One of the great ironies of the healthcare system is that doctors are often untrained in the most basic of wellness practices: nutrition. In a survey of 236 physicians at a large US medical center (including cardiologists and internal medicine doctors and trainees), fewer than 14% felt adequately trained to discuss nutrition with their patients. Nearly all doctors (90%) recognized the Mediterranean Diet as protective against heart disease, but fewer than half (46%) realized that low-fat diets have not been proven to reduce heart disease risk. Additionally, many doctors had trouble identifying foods high in various nutrients, such as which fish are high in omega-3 fatty acids. These data highlight the importance of making reliable nutrition resources (specifically those relating to well researched eating patterns, such as the Mediterranean diet) available to the medical community. (Note: If you’re a healthcare professional who would like to learn more about the Mediterranean Diet, see here.)
Presentation at the American College of Cardiology’s 64th Annual Scientific Session. San Diego CA. March 15, 2015. 

Plant-Based Diets May Reduce Colorectal Cancer Risk

Colorectal cancer is the leading cause of cancer mortality, so learning more about dietary prevention is an important area of research. Scientists at Loma Linda University in California analyzed food patterns and health data from over 77,000 adults for an average of 7 years. After controlling for demographic and lifestyle factors (including age, smoking, physical activity, and family history), the researchers found that those who ate vegetarian diets had an approximately 20% lower risk of colorectal cancer compared with nonvegetarians. Researchers also found that pesco-vegetarians in particular (vegetarians who eat fish) had a much lower risk of colorectal cancer. These results support other studies linking the Mediterranean diet (a plant-based diet that features fish) with a decreased risk for colorectal cancer.
JAMA Internal Medicine. 2015 March 9. [Epub ahead of print] (Orlich MJ et al.)

Cardioprotective Effect of Mediterranean Diet

Ventricular hypertrophy, or the thickening and enlargement of heart ventricles due to the accumulation of scar tissue, is thought to be a root cause of many heart ailments. To investigate how diet relates to this condition, researchers analyzed eating patterns and left ventricular mass (the size of the left ventricle of the heart, where enlargement is most common) of over 1,700 adults without history of heart attack or stroke. The scientists found that those most closely adhering to a Mediterranean Diet had a left ventricular mass that was 4% less than the rest of the study population, a reduction greater than that observed in people with moderate-to-heavy physical activity (another factor that supports heart health). In fact, for each point increase on the Mediterranean Diet Score (0-9), left ventricular mass was 1.98g lower (average left ventricular mass was 189g).
American Journal of Cardiology. 2015 Feb 15;115(4):510-4. (Gardener H et al.)

Med Diet May Reduce Alzheimer’s Risk by Half

The Mediterranean diet, famous for its link with healthy aging, may also cut the risk for Alzheimer’s. Researchers studied the relationship between eating patterns and Alzheimer’s in 923 retired adults in Chicago over an average of 4.5 years.  The scientists rated participants’ diets based on how closely they adhered to the Mediterranean diet, the DASH diet (a healthy diet used to treat hypertension that emphasizes fruits, vegetables, whole grains, low fat dairy, and limited sweets and salt) and the MIND diet. The MIND diet is a hybrid Mediterranean-DASH diet that emphasizes foods associated with brain health, including whole grains, green leafy vegetables, berries, nuts, olive oil, and fish. Those most closely following the Mediterranean diet were 54% less likely to develop Alzheimer’s dementia (more than any other diet group). Comparatively, those most closely following the DASH diet were 39% less likely to develop Alzheimer’s dementia. The group most closely following the MIND diet (which shares many similarities with the Med diet) was 53% less likely to develop Alzheimer’s dementia than the group with the lowest MIND diet scores, and even those moderately following the MIND diet were at a 35% lower risk. 

Alzheimer’s and Dementia. 2015 Feb 11. pii: S1552-5260(15)00017-5. [Epub ahead of print] (Morris MC et al.)

Antioxidant in Olive Oil has Anti-Cancer Properties

A worthy star of the Mediterranean diet, olive oil gains much of its prestige from the various antioxidants that it contains. To see how one of these antioxidants affects cancer growth, New York scientists extracted oleocanthal (OC), a compound in extra virgin olive oil, and applied it to a variety of cancer cells.  According to the scientists, “Amazingly, OC induced cell death in all cancer cells examined – as rapidly as 30 minutes after treatment,” but did not cause cell death in noncancerous cells. This finding opens up a new field in the area of cancer research, as scientists are eager to find more ways to treat and prevent this devastating disease. While guzzling olive oil is by no means a cure for cancer, these findings support existing research that enhancing your meals with olive oil is a delicious and nutritious practice to build a long and healthy life.
Molecular and Cellular Oncology. 2015 Jan 23. [Epub ahead of print] (LeGendre O et al.)

Mediterranean Diet Associated With Healthy Aging, DNA

Telomeres, DNA sequences at the end of chromosomes, can tell us a lot about aging and longevity, as shorter telomeres are associated with many age related diseases, such as heart disease and cancer. To determine the relationship between DNA and diet, Harvard researchers analyzed food intake and telomere length from over 4,600 healthy nurses using data from the Nurses’ Health Study. Researchers found that people with the greatest adherence to the Mediterranean Diet (lots of vegetables, fruits, grains (mostly unrefined), fish, legumes, and nuts, and less meat) had the longest telomeres, a good indicator of healthy aging. Additionally, the scientists pointed out that no one specific food was pinpointed as the best, reinforcing the importance of a well-rounded, healthy diet.
British Medical Journal. 2014 Dec 2;349. (Crous-Bou M et al.)

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